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This book covers all liver tumors and lesions that clinically and radiologically mimic liver tumors. ItÂ provides readers with a comprehensive overview of this complex and rapidly evolving field. AllÂ aspects of surgical pathology are addressed, supplemented by detailed presentations of the lesionsâÂ cell-biologic and molecular features. In addition, the methods employed for diagnosis and diagnosticÂ algorithms are discussed. It appeals to pathologists and hepatologists and serves as an invaluable aidÂ to diagnosis.
The field of liver tumors and tumor-like lesions in adults and children has experienced tremendousÂ advances in recent years. Specifically, the recognition of novel entities, deepened insights into knownÂ tumors, and refinement of classifications have necessitated continual updates and reappraisals. InÂ addition, previous understanding of hepatic carcinogenesis and tumor progression has beenÂ transformed by the very rapid evolution of our understanding of cell biology, genomics, signalingÂ pathways, cell interactions, and mechanisms of invasion and spread of hepatic tumor cells. TheseÂ general pathology issues must be combined with surgical pathology if a comprehensiveÂ understanding of liver tumor pathology is to be achieved.