Amazon.com description: Product Description: In 1965, neuroscientist Margot Sharpe meets Elihu Hoopes -- the ''man without a shadow'' -- whose devastated memory, unable to store new experiences or to retrieve the old, will make him the most famous and most studied amnesiac in history. Over the course of the next thirty years, Margot herself becomes famous for her experiments with E. H.""and inadvertently falls in love with him. Oates tracks the intimate, illicit relationship between Margot and Eli, as scientist and subject embark upon an exploration of mysteries of the human brain. Where does ''memory'' reside? Where is ''love''? Is it possible to love an individual who cannot love you, who cannot ''remember'' you from one meeting to the next?