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By
Roger H. Kennett (editor)
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Bibliographic Detail
Publisher
Springer Verlag
Publication date
March 30, 2012
Binding
Paperback
Edition
Reprint
Book category
Adult Non-Fiction
ISBN-13
9781461575078
ISBN-10
1461575079
Dimensions
0 by 7 by 10 in.
Original list price
$99.00
Other format details
medical
Summaries and Reviews
Amazon.com description: Product Description: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity. " Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid oma technology has been observing how the implications of the initial observa tions gradually spread first among the practitioners of immunology and immu nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.
Editions
Hardcover
from Plenum Pub Corp (August 1, 1980)
9780306404085 | details & prices | List price $119.50
Paperback
The price comparison is for this edition
Reprint edition from Springer Verlag (March 30, 2012); titled "Monoclonal Antibodies: Hybridomas: a New Dimension in Biological Analyses"
9781461575078 | details & prices | List price $99.00
About: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity.
About: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing "Continuous cultures of fused cells secreting antibody of predefined specificity.
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