Amazon.com description: Product Description: This volume presents molecular and genetic studies that shed new light on the pathogenesis of these diseases. The contributors show how molecular and genetic analyses of mitochondria can explain the variable clinical features of mitochondrial encephalomyopathies and provide a basis for classifying these diseases. Several studies link mutations or deletions affecting mitochondrial respiratory disorders, myoclinic epilepsy, idiopathic cardiomyopathy, and other disorders. The book also describes therapeutic trials with CoQ10 for mitochondrial myopathies.