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: This report is one of five volumes providing detailed information on the QA Tools, RAND's comprehensive, clinically based system for assessing quality of care for children and adults. The QA Tools indicators encompass screening, diagnosis, treatment, and follow-up in 46 clinical areas and cover a variety of modes of providing care, including history,physical examination, laboratory study, medication, and other interventions and contacts. Development of each indicator was based on the ratings of a panel of experts in the relevant fields and on a focused review of the scientific literature, which is clearly documented for each clinical condition. This volume focuses on indicators for care of oncologic conditions and HIV. Each chapter summarizes the results of the literature review for a particular condition, provides RAND staff's recommended indicators based on thatreview, and notes the level of scientific evidence supporting each indicator along with the relevant citations. In addition, this work details the process by which the expert panel evaluated the indicators and the final disposition of each indicator. Clinical conditions covered in this volume are: Breast cancer, cervical cancer, colorectal cancer, HIV, lung cancer, prostate cancer, skin cancer, cancer pain and palliation. Other RAND Health titles on the QA Tools system focus on indicators for care of children and adolescents, general medical conditions, cardiopulmonary conditions, and women.