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Dietary Reference Intakes: Applications in Dietary Assessment
By Maria Elena Buszek, Ph. D. (foreword by), Mike Madrid (compiler) and Institute of Medicine (editor)
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Jump down to see edition details for Dietary Reference Intakes: Applications in Dietary Assessment: Paperback
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Bibliographic Detail
Publisher Natl Academy Pr
Publication date May 1, 2001
Binding Paperback
Book category Adult Non-Fiction
ISBN-13 9780309073332
ISBN-10 0309073332
Original list price $34.95
Summaries and Reviews
Amazon.com description: Product Description:

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false.

Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.



Editions
This edition contains multiple works--typically stories or entire novels--that are found in different collections. Below find each work in this edition grouped by how you can find each.
Paperback
Book cover for 9780309073332
 
The price comparison is for this edition
With Mike Madrid (other contributor), Maria Elena Buszek, Ph. D. (other contributor) | from Natl Academy Pr (May 1, 2001)
9780309073332 | details & prices | List price $34.95
This edition also contains Divas, Dames & Daredevils: Lost Heroines of Golden Age Comics
About: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition.
Paperback
Book cover for 9780309073332 Book cover for 9781935259237
 
from Exterminating Angel Pr (October 15, 2013)
9781935259237 | details & prices | 236 pages | 7.00 × 9.00 × 0.50 in. | 1.00 lbs | List price $16.95
About: ComicsAlliance and ComicsBlend Best Comic Book of the YearBUST Magazine “Lit Pick” RecommendationCertified Cool™ in PREVIEWS: The Comic Shop’s Catalog“Mike Madrid gives these forgotten superheroines their due.
The price comparison is for this edition
With Institute of Medicine (other contributor) | from Natl Academy Pr (May 1, 2001); titled "Dietary Reference Intakes: Applications in Dietary Assessment"
9780309073332 | details & prices | List price $34.95
This edition also contains Dietary Reference Intakes: Applications in Dietary Assessment
About: Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition.

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