America's Civil War and violent attempts by the Indians to regain their land in Minnesota force the Nilsson family--emigrants from Sweden and now citizens--to demonstrate their strength and courage once again

Product Description: The premise of Quality by Design (QbD) is that the quality of the pharmaceutical product should be based upon a thorough understanding of both the product and the manufacturing process. This state-of-the-art book provides a single source of information on emerging statistical approaches to QbD and risk-based pharmaceutical development...read more

This Handbook is a reference for all aspects of the field of health services and outcomes research. It addresses the increasing need for comprehensive, yet balanced, information in a field that welcomes various disciplines: medicine, public health, statistics, economics, management, policy, and information technology. This well-organized reference is an indispensable source of information for everyone who seeks to develop understanding of health systems and to learn about historical, political, and socioeconomic factors that influence health policies at the global, national, regional and local level. Specifically, the Handbook helps readers: Recognize core concepts of health services and outcomes research, such as, need, access, equity, quality and safety; Become familiar with social, political, organizational, behavioral and economic theories that have influenced health systems designs; Learn about frameworks developed for evaluating the organization, financing, delivery, utilization and outcomes of health services; Get an introduction to methods of comparative effectiveness research, program evaluation, health technology assessment and health economics; Identify types and sources of data appropriate for generating valid and reliable information about the delivery of health services; Learn about strengths and weaknesses of various research designs used to study health services and policy issues. The online version of Health Care Systems and Policies is in the format of a dynamically updated knowledge base, offering search tools, cross-referencing across chapters and linking to supplement data, other major reference works and external articles. The Handbook is accessible at the level of graduate students even if it is not their focus area. This includes students with various backgrounds: medicine, public health, statistics, economics, management or information technology.

Product Description: The Handbook of Health Services Research is a reference for all aspects of the field of health services and outcomes research. It addresses the increasing need for comprehensive, yet balanced, information in a field that welcomes various disciplines: medicine, public health, statistics, economics, management, policy, and information technology...read more

This book presents a systematic and comprehensive treatment of various prior processes that have been developed over the last four decades in order to deal with the Bayesian approach to solving some nonparametric inference problems. Applications of these priors in various estimation problems are presented. Starting with the famous Dirichlet process and its variants, the first part describes processes neutral to the right, gamma and extended gamma, beta and beta-Stacy, tail free and Polya tree, one and two parameter Poisson-Dirichlet, the Chinese Restaurant and Indian Buffet processes, etc., and discusses their interconnection. In addition, several new processes that have appeared in the literature in recent years and which are off-shoots of the Dirichlet process are described briefly. The second part contains the Bayesian solutions to certain estimation problems pertaining to the distribution function and its functional based on complete data. Because of the conjugacy property of some of these processes, the resulting solutions are mostly in closed form. The third part treats similar problems but based on right censored data. Other applications are also included. A comprehensive list of references is provided in order to help readers explore further on their own.