Product Description: UP-TO-DATE PRACTICAL GUIDE TO LEUKAEMIA DIAGNOSIS Written by a renowned expert this practical guide had been fully revised and updated. The book covers recent advances in the fields of immunophenotyping, cytogenetics and molecular genetics...read more

Now in its third edition Leukaemia Diagnosis has been completely revised and updated throughout to include the latest developments in the fields of haematology and oncology. Written by Barbabra Bain, an acclaimed haematologist and morphologist, Leukaemia Diagnosis is a highly practical guide and reference source, which reflects the latest changes in the fields of morphology, cytochemistry, immunophenotyping, cytogenetics and molecular genetics. The third edition of Leukaemia Diagnosis includes: Over 180 superb four-colour photographs of normal cells and abnormal variants The latest WHO leukaemia classification guidelines

When his father finally says he can get a pet, George, a little boy who has everything, searches high and low for the perfect companion--with hilarious results!

Product Description: Leukaemia is a very heterogeneous group of diseases with a variety of causes, disease processes and outcomes. Accurate diagnosis and classification will ultimately determine the choice of therapy and possible disease outcome for the patient...read more (view table of contents, read Amazon.com's description)

Product Description: Great information textbook/guide!

Product Description: Covers morphology and cytochemistry, the cornerstones of diagnosis, and contains 21 case studies with nearly 90 full-color photomicrographs.

Relapse of leukemia following successful remission-induction therapy remains a major obstacle in the treatment of patients with acute leukemia. Leukemia recurs most frequently in patients with acute myeloblastic leukemia (AML) and high risk acute lymphoblastic leukemia (ALL) following chemotherapy and less often in patients with low risk ALL and particularly in patient groups> submitted to allogeneic marrow transplantation. ' It is likely that the great majority of these recurrences originate from residual leukemic cells that survive initial remission-induction chemotherapy. Today, several research groups throughout the world place emphasis on studies concerned with the detection and treatment of 'minimal residual disease' (MRD). These investigations are conducted with the common objective to tackle the remaining cells. 'Minimal Residual Disease in Acute Leukemia: 1986' summarizes the fast advancements in this area. Several disciplines are concerned with the analysis of leukemic cells. The perspectives of cytogenetic and molecular genetic approaches for applica­ tion in the detection of MRD are reviewed. In this respect, modern cyto­ genetics provide highly specific tumor markers. The resolution of cyto­ genetic methods can be particularly improved when combined with other techniques which select relevant subpopulations of cells. Characterization of oncogenes and gene rearrangements, including those of immunoglobulin and T-cell receptor genes, and the measurement of gene products, have been established. Techniques based on these approaches offer interesting tools for the detection of MRD. New possibilities of employing monoclonal anti­ bodies are also presented.

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Product Description: The objective of the treatment of acute leukemia involves the eradication of all neoplastic cells, including the last one. Ideally, treatment should be controlled by monitoring cell kill. If the last cells could be discovered and their biological properties be determined, the qualitative and quantitative effects of treatment should be directly evaluable...read more