This volume is a collection of chapters contributed by leading experts in the emerging field of analytical morphology. Its contents cover a wide range of techniques for morphologic research and diagnosis and it is intended for anyone who wants to keep abreast of the rapid development in this field. Analytical morphology is a contemporary science dealing with the analy- sis of shape, size and color arrangement of cell and tissue components by means of a variety of analytical maneuvers. It differs from conventional mor- phology and histopathology in that it employs methods beyond routine hema- toxylin and eosin or histochemical staining. To a great extent, the advance- ment of analytical morphology is based on new advances in other disciplines, such as immunology, molecular biology, laser technology, microwave tech- nology and computer science. Using these new methods, particular cellular components that would otherwise remain invisible, such as peptides, pro- teins, or nucleotide sequences, are highlighted by visible markers through chemical, physical, immunological or molecular biological reactions. These methods include immunocytochemistry, in situ hybridization, in situ poly- merase chain reaction, antigen retrieval, image analysis, and the like. Analytical morphology is the foundation of contemporary medicine. It provides concrete and visible evidence for many conceptual deductions of other life science disciplines.

Product Description: Pathology is an inherently subjective discipline, and therefore is often referred to as both an art and a science. Over the years, laboratory physicians have implemented special tissue stains and molecular techniques to limit subjectivity in the discipline...read more

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Product Description: Practical, and intended for day-to-day use, this state-of-the-art New Edition presents the elements of immunohistochemistry in the context of the "total test". It deals logically with issues of test selection · reagent selection and quantification · protocols and methods · controls · results · interpretation · in situ hybridization · reporting · and significance...read more

Product Description: Immunogold silver staining is one of the most sensitive techniques available for visualizing the location of antibodies and nucleotide probes that have been bounded to specific antigens or to nucleotide sequences. As gold and silver staining continues to advance research in molecular morphology, this book presents the information you need to know about the various staining methods, their useful applications, and the advantages and drawbacks of each process...read more (view table of contents, read Amazon.com's description)

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Product Description: Written by molecular biologists and neurobiologists, this volume in the Handbook Series provides basic step-by-step protocols in addition to specialist techniques to support those practising in situ hybridization, a powerful histochemical technique which is now widely used in neurobiology...read more (view table of contents, read Amazon.com's description)

Product Description: Leading international experts describe both novel and established immunohistochemical techniques and interpret results and validity regarding the various methods used, particularly in the investigation of the nervous system. Coverage includes the immunocytochemistry (ICC) of second messenger molecules, applications of confocal microscopy to ICC, the latest pre-embedding and dual labeling EM techniques, anterograde PHAL tracing and more...read more (view table of contents, read Amazon.com's description)