Product Description: Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes...read more (view table of contents, read Amazon.com's description)

Product Description: This volume covers both the basic and translational/clinical aspects of this molecular family, focusing on its role in the differentiation, selection, and regulation of primary and antigen-experienced B cells. In addition, clinical aspects are detailed.

Product Description: The importance of specific antibodies for the clearance of and long-term resistance to many infectious pathogens has long been appreciated. In the last five years, data from these areas of research has coalesced, resulting in the emergence of a new and more complete understanding of how antibody-mediated resistance to pathogens is elaborated...read more

Product Description: The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation...read more

Product Description: The understanding of B cell biology has increased and expanded enormously in the last three decades. It is now known that B cells, in addition to just differentiating into antibody-secreting cells, serve many other vital functions...read more

Product Description: B cells play a central role not only in adaptive immunity, but also in autoimmunity. To understand how B cells are normally prevented from reacting to self-tissue, what goes wrong in autoimmunity, and how B cells contribute to it is the aim of this book...read more (view table of contents, read Amazon.com's description)

Product Description: Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. In this regard, Band T lymphocytes, which comprise the two arms of the antigen-specific and inducible immune system, though functionally very different, are descendants of the same stem cell precursor...read more (view table of contents, read Amazon.com's description)

Superantigens are a rapidly growing new class of ligands for human B-cells. The study of their interaction with lymphocytes provides insight into important mechanisms of the immune system. In this book, leading scientists survey the progress recently made in the identification, the nature, the structure of B-cell superantigens and their potential involvement in pathological conditions. It is the first book to bring together a comprehensive view of the recently described B-cell superantigens.

Product Description: This book is about the involvement of B cells in autoimmune diseases through both the production of autoantibodies and their participation in antigen presentation and immune regulation. Autoantibodies are used as biological markers of various autoimmune diseases in clinical practice...read more

Product Description: To compile this up-to-date handbook, Dr. Charles Snow of the University of Kentucky Medical Center has assembled works by a premier group of active investigators who meet the needs of todays researchers. The handbookprovides a broad overview of the historical and current research in B- and T-cell biology, and presents the latest developments in this fast-breaking field to all professionals concerned with the humoral immune response of the body...read more

Product Description: This book provides an analysis of the current subdisciplines comprising the study of humoral immune response. The first chapter presents a detailed discussion regarding the experimental and conceptual studies conducted prior to the mid-1970s that have served as a valuable research framework for investigators interested in the process by which B cells are activated following their exposure to antigens...read more

Product Description: This book provides a timely review of our current knowledge of the cellular and molecular biology of B lymphocytes. These cells play a key role in the immune system. B cells recognize antigens by means of specific cell surface antibody molecules, and in recent years there has been rapid progress in our understanding of these responses...read more